Rxf393
WebCB-002 CB002 61034-15-9 A novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts. supplier price datasheet IC50 chemical structure probechem inhibitor WebRXF393 Xenograft Model; Liver Cancer Xenografts. H22 Allograft Model; Hepa 1-6 Allograft Syngeneic Model; Hep3B Xenograft Model; HepG2 Xenograft Model; Huh7 Xenograft …
Rxf393
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http://ezbiosystems.com/view2.asp?d_id=321 WebLucitanib is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively). All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use. Lucitanib, CAS 1058137-23-7
WebHuman Kidney Renal Cell Carcinoma RXF393 Whole Cell Lysate can be used for research. Human Kidney Renal Cell Carcinoma RXF393 Whole Cell Lysate RXF393-027WCY HOME PRODUCTS Recombinant Proteins PROTAC Targets Full Length Protein Monkeypox Virus-related Proteins Fluorescent-labeled Recombinant Proteins Avi-tag Biotinylated Proteins … WebMay 2, 2016 · ( d) Representative micrographs of H&E histology ( n = 10) of quadriceps muscles in RXF393 (RXF)-bearing mice, relative to SKRC39 (SKR)-bearing mice. Scale bars, 200 μm. ( e) Quantification of...
WebRXF393-induced cachexia is prevented by sunitinib treatment independently from tumor inhibition. A, RXF393 cells were injected subcutaneously into the flank of nude mice: … WebThe RXF393 xenograft model has been used to study pancreatic cancer treatments (lapatinib, S-1, small molecule inhibitors, immunotherapies, etc.). Basic Study Design. …
WebStatus: Public on Oct 08, 2016: Title: RXF393: Sample type: genomic : Source name: Kidney: Organism: Homo sapiens: Characteristics: tissue: Kidney cell line: RXF393
WebThe tumor composed of the RXF393 cell line induced cachexia in the host, leading to a moribund condition, even when the primary tumor was small (green dashed circle). The tumor composed of the ... heart bird feederWebR175H p53 expression was rescued by addition of proteasome inhibitor MG132 to CB002, suggesting a role for ubiquitin-mediated degradation of the mutant protein. In summary, CB002, a p53 pathway-restoring compound that targets mutant p53 for degradation and induces tumor cell death through NOXA, may be further developed as a cancer therapeutic. heart birdmountain with path clipartWebCell Line: RXF393 Link to Cell Model Passport. Dataset. GDSC2 GDSC1. Drug Targets Z score; The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the … heart bird feeder craftWebApr 24, 2013 · (E) A renal cell carcinoma line, RXF393, was also profiled by exon microarray where an expression breakpoint was evident within CLTC. ***P10−9(Student's t-test). History Usage metrics Read the peer-reviewed publication Breakpoint Analysis of Transcriptional and Genomic Profiles Uncovers Novel Gene Fusions Spanning Multiple Human Cancer … heart bird foodWebFeb 20, 2015 · We used the RXF393 human renal carcinoma xenograft that recapitulates the characteristics of the disease, including the growth in the mouse kidney (orthotopic … mountain with fieldWebRXF393-027WCY Optional Service: Optional requirements on this protein: Product Overview : RXF393 (Human Kidney Renal Cell Carcinoma) Whole Cell Lysate: Description : XF393 cell … mountain with friends quotes