Web27 iun. 2024 · Multiple myeloma (MM) is a plasma cell disorder characterized by clonal proliferation of malignant plasma cells producing … WebThe aetiology of renal damage is multifactorial, but increased production of free light chains that are filtered into the urine is crucial for the development of renal failure and could be …
Kidney disease in multiple myeloma and other monoclonal
Web21 mai 2024 · Multiple myeloma (MM) is the second most common hematologic malignancy and is associated with substantial patient burden 1. Despite the introduction of newer agents, patients with MM continue... WebRenal failure is a serious complication of multiple myeloma, and up to 50% of patients with this most frequent haematological malignancy may develop some form of renal impairment. The aetiology of renal damage is multifactorial, but increased production of free light chains that are filtered into th … streets viennetta birthday cake
Renal impairment in patients with multiple myeloma: a …
WebAlthough creatinine remains the best clinical marker of kidney function, there are multiple limitations to its use as a marker of kidney function, especially in the non-steady states that characterize AKI. ... The AKI seen in myeloma kidney is in part attributable to the renal toxicity of light chains. Antibiotics, particularly aminoglycosides ... Web27 feb. 2024 · Kidney disease is a common complication of multiple myeloma and other monoclonal gammopathies (paraproteinemias). A wide range of kidney manifestations and pathologies involving different mechanisms have been described with these disorders. WebMultiple myeloma can affect the kidney in several ways. It can affect the filter (glomerulus), the tubules (pipes), or the tissue of the kidney itself (interstitium). … streets won\u0027t forget meaning