Mouse srsf3
Nettet23. jun. 2024 · e–f Co-immunofluorescence staining of PTBP2 (e) and SRSF3 (f) with SYCP3 in testis sections from adult control and hnRNPH1 cKO mice. The DNA was … NettetScrolling left and right on the mouse as well as up and down is a feature I never thought I needed until now. 6. Share. Report Save. level 2 · 7y. Surface Pro 3 - 128GB / Intel i5. …
Mouse srsf3
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Nettet3. sep. 2015 · Gene silencing techniques are widely used to control gene expression and have potential for RNAi-based therapeutics. In this report, transgenic mouse lines were created for conditional knockdown... NettetSerine-rich splicing factor 3 (SRSF3) was recently reported as being necessary to preserve RNA stability via an mTOR mechanism in a cardiac mouse model in adulthood. Here, …
http://www.informatics.jax.org/allele/MGI:2669749 Nettet13. apr. 2024 · To better understand the functional difference between high ploidy LCM and SCM, we utilised a mouse model (Supplementary Fig. 1g, MK-LCM Δ/Δ, Pf4-Srsf3 Δ/Δ mice) with normal incidence and ...
NettetDescription. Srsf3 is located on chromosome 17 of mice. Using CRISPR/Cas9 technology, sgRNA and ssDNA are designed, and Srsf3 gene conditional knockout mice are obtained through high-throughput electrotransformation of fertilized eggs. After sexual maturity, sperms are taken and frozen. Strain. C57BL/6J-Srsf3. Strain No. CKOCMP-20383 … Nettet26. feb. 2024 · Furthermore, the SRSF3 knockout mice all developed HCC with aging . SRSF3 was found to be downregulated in human HCC samples, and recent studies showed SRSF3 was also reduced in NAFLD, NASH and cirrhosis liver samples in both human and mouse, and as a consequence, changes in the splicing of known SRSF3 …
Nettet31. jan. 2024 · We identified hnRNPM and SRSF3 as key factors required to suppress exon 6A inclusion and maintain high DHX9 expression in Ewing sarcoma cells. Importantly, downregulation of SRSF3 or hnRNPM sensitized Ewing sarcoma cells to doxorubicin, a genotoxic agent used in Ewing sarcoma chemotherapy.
Nettet16. aug. 2004 · P84104 · SRSF3_MOUSE. Protein. Serine/arginine-rich splicing factor 3. Gene. Srsf3. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mus musculus (Mouse) Amino acids. 164. ... a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements … the good fork pubNettet29. sep. 2015 · It has been reported that SRSF3 regulates its own expression by enhancing the inclusion of exon 4 in mouse cells. Since exon 4 has an in-frame pre-mature stop codon, inclusion of this exon... the good fork menuNettetMouse anti SRSF3 antibody recognizes serine/arginine-rich splicing factor 3, also known as SFRS3, SRP20. SRSF3 is the smallest member of the SR family of proteins, and promotes RNA splicing by recruiting spliceosome components. theaters termsNettetAll lanes : Anti-SRSF3 antibody [EPR16976] (ab198291) at 1/1000 dilution Lane 1 : Mouse brain lysate Lane 2 : Rat brain lysate Lane 3 : C6 (Rat glial tumor) whole cell lysate Lane 4 : RAW 264.7(Mouse macrophage cells transformed with Abelson murine leukemia virus) whole cell lysate Lane 5 : PC-12 (Rat adrenal gland pheochromocytoma) whole cell … theaters terre hauteNettet23. jun. 2024 · IgG was used as a negative control. e Co-immunofluorescence staining of PTBP2 (left panels) and SRSF3 (right panels) with hnRNPH1 in adult mouse testes. P pachytene spermatocytes, RS round... theater sterz kaindorfNettetSRSF3 is phosphorylated at AKT consensus sites downstream of PI3K‑mediated platelet‑derived growth factor receptor α signaling in mouse palatal mesenchymal cells, resulting in its nuclear translocation (56). However, SRSF3 appears to be hypo‑phosphorylated and stable in cells(57), which may be a way to maintain cell … the good fork nyNettetUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. theater steppenwolf