Web8 apr. 2024 · Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with clinical features of high metastatic potential, susceptibility to relapse, … Web1 jun. 2024 · Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences Oncotarget , 9 ( 2024 ) , pp. 11677 - …
Metabolic clusters of breast cancer in relation to gene- and …
WebBreast cancer in relation to metabolic factors Table 4. Relative risk of breast cancer by quartiles of selected metabolic factors Category Incident cases Person-years RRa (CI 95%) P for trend Premenopausal Cholesterol <4.61 28 15144 1.00 0.49 >4.61- <5.35 28 18383 0.72(0.42-1.21) Web1 apr. 2024 · Triple-negative tumor cells, a malignant subtype of breast cancer, lack a biologically targeted therapy. Given its DNA repair inhibiting properties, caffeine has been shown to enhance the effectiveness of specific tumor chemotherapies. In this work, we have investigated the effects of caffeine, cisplatin, and a combination of the two as potential … the vine valleywise
Metabolic approaches to breast cancer treatment and …
WebBreast cancer cells are well documented to reprogram their metabolism via mutations or inactivation of intrinsic factors such as c-Myc, TP53, hypoxia-inducible factor, and the … Web29 sep. 2024 · Metabolic reprogramming is being recognized as a fundamental hallmark of cancer, and efforts to identify drugs that can target cancer metabolism are underway. In this study, we used human breast cancer (BC) cell lines and established their invading phenotype (INV) collected from transwell inserts to compare metabolome differences and … Web13 apr. 2024 · The stromal target cells of tumor cell-derived EVs are mainly fibroblasts, which dynamically regulate each other in the tumor microenvironment, diverse HNSCC-derived EVs cargoes, such as nucleic... the vine untangled