WebNov 21, 2024 · This study aimed to select the feature genes of hepatocellular carcinoma (HCC) with the Fisher score algorithm and to identify hub genes with the Maximal Clique Centrality (MCC) algorithm. Gene ... WebFeb 10, 2024 · The maximal clique centrality (MCC) method screened the hub genes. Survival analysis Gene expression profiling interactive analysis (GEPIA) ( http://gepia.cancer-pku.cn) allows users to interact with …
Cytoscape + STRING + cytoHubba 联合使用寻找hub基因 - 简书
WebApr 28, 2024 · 1、首先选择左边的 cytoHubba 进入工作页面 2、 Target Network 选择待分析的网络 3、点击 Calculate 4、点击 Top 10 ,可根据自身课题需要,调整提取关键基因的数量 5、下方 MCC 可下拉选择计算方法 6、 Particular nodes :选择感兴趣的基因进行分析(一般是对整个网络分析的话,此项可以忽略) 5、点击左下方 Display the shortest path :显 … WebIn a co-expression network, Maximal Clique Centrality (MCC) algorithm was reported to be the most effective method of finding hub nodes . The MCC of each node was calculated … bjp general secretary national
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WebNov 20, 2024 · The hub gene of top 100 was obtained by MCC method of cytohubb and were imported into Cytoscape to construct the protein–protein interaction (PPI) network. In addition, we used R package clusterProfiler (version 3.16.1) [ 26 ] to analyze the statistical enrichment of miRNA-target genes in GO and KEGG. WebTo download clusterMaker using the plugin manager, you must be running Cytoscape 2.8.2 or newer. clusterMaker is available in the Analysis group of plugins. To install it, bring up … WebJan 14, 2024 · 23 Citations Metrics Abstract Gastric cancer (GC) is one of the most common types of malignancy. Its potential molecular mechanism has not been clarified. In this study, we aimed to explore... dating app for white guys