WebJul 2, 2024 · Overexpression of circEIF4G3 suppressed GC growth and metastasis through the inhibition of \u03b2-catenin signaling, whereas knockdown of circEIF4G3 showed the opposite effects. Mechanistic studies revealed that circEIF4G3 bound to \u03b4-catenin protein to promote its TRIM25-mediated ubiquitin degradation and interacted with miR … WebDownload scientific diagram CircEIF4G3 functions as a miR-4449 sponge. (A) RIP assay was applied using Ago2 antibody in GC cells. The relative RNA level of circEIF4G3 was detected by qRT-PCR.
Circular RNA EIF4G3 suppresses gastric cancer ... - Molecular Cancer
WebResults Downregulated expression of circular RNA EIF4G3 (circEIF4G3; hsa_circ_0007991) was found in GC and was associated with poor clinical outcomes. Overexpression of circEIF4G3 suppressed GC growth and metastasis through the inhibition of β-catenin signaling, whereas knockdown of circEIF4G3 showed the opposite effects. WebAug 22, 2024 · This study found that CircEIF4G3 was down-regulated in gastric cancer patients and predicted poor prognosis. CircEIF4G3 destabilizes δ-catenin by forming a … chunk border pack
Circ-EIF4G3 promotes the development of gastric cancer by
Webhsa_circEIF4G3_060. Last modified by: XXH Created Date: 4/29/2024 8:53:00 AM Other titles: 交集的circRNA Sheet2 ... WebAug 10, 2024 · The formation of a unique back-splice junction (BSJ) differentiates the circRNAs from their linear counterpart. CircRNAs are highly expressed in the central nervous system where many of them are regulated during development 1 – 3, inflammation 4, and also found to function as biomarkers in cancer 5 – 7. WebBackground: Circular RNAs (circRNAs), a new group of endogenous non-coding RNAs, plays a crucial role in various types of carcinomas. However, there is still limited … detected project binding: nonexistent